A roller die cutter is far and away the biggest time saver when skin packaging. It takes the chore of cutting apart the packaged sheet, rounding the corners and adding a hang hole from many minutes down to seconds.
A steel rule die is made in the shape and size of the desired card size and layout. The die consists of knife bent into the shape of the card and hang holes set into a layer or layers of wood with a steel backing. Cavities are cut out of the middle of each card to ensure that your product isn't crushed.
A packaged sheet in set, face down, on top of the cutting knife. The sheet is located using spring loaded pins around the perimeter of the sheet. After a plastic plate is put on top of the paper to act as an anvil, the die "sandwich" is pushed through the cutter.
2 rollers apply pressure while turning and pull the die through the machine. When the sheet comes out the other side. You have perfectly cut individual skin cards including round corners and hang holes if wanted.